RBM42

Across TCGA cell cohorts, RBM42 mutation is significantly associated with the RNA expression of many other genes, with 140 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RBM42-associated genes across cancer lineages are IFNA4, CBY1, and PHF5A. Each is linked with RBM42 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM42-to-partner and partner-to-RBM42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA4 grouped by RBM42-low versus RBM42-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM42→partner) and Y-score (partner→RBM42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IFNA4 →	+0.055	+4.922	<.001	.009	3	1
LARGE_INTESTINE	CBY1 →	+0.664	+3.451	<.001	.002	3	1
LARGE_INTESTINE	PHF5A →	+0.481	+3.364	.009	.002	3	1
LARGE_INTESTINE	ASPN →	+0.028	+2.600	.008	.006	3	1
LARGE_INTESTINE	CUEDC2 →	+0.615	+3.064	.002	.009	3	1
LARGE_INTESTINE	ACBD5 →	+0.721	+3.364	.007	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 140 associations by consensus.

IFNA4 by RBM42 expression — BLOOD_Leukemia

Explore this box plot interactively →