RBM41

Across TCGA cell cohorts, RBM41 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RBM41-associated genes across cancer lineages are WDR87, MSGN1, and TAFA1. Each is linked with RBM41 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM41-to-partner and partner-to-RBM41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WDR87 grouped by RBM41-low versus RBM41-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM41→partner) and Y-score (partner→RBM41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	WDR87 →	+0.023	+4.209	<.001	.006	3	1
LARGE_INTESTINE	MSGN1 →	+0.126	+4.930	<.001	.001	3	1
LARGE_INTESTINE	TAFA1 →	+0.410	+4.273	<.001	.006	3	1
LARGE_INTESTINE	BTNL2 →	+0.081	+4.415	<.001	.007	3	1
LARGE_INTESTINE	MS4A18 →	+0.028	+4.095	<.001	.009	3	1
LARGE_INTESTINE	TEX53 →	+0.134	+4.684	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

WDR87 by RBM41 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →