RBM4

Across TCGA cell cohorts, RBM4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,569 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RBM4-associated GO terms across cancer lineages are Positive regulation of gene expression, epigenetic, Transcription initiation at RNA polymerase II promoter, and Protein-DNA complex organization. Each is linked with RBM4 in more than 14 cancer types. Because this analysis shows association rather than direction, both RBM4-to-partner and partner-to-RBM4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of gene expression, epigenetic grouped by RBM4-low versus RBM4-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM4→partner) and Y-score (partner→RBM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of gene expression, epigenetic →	+0.057	+0.580	.009	.001	3	15
STOMACH	Transcription initiation at RNA polymerase II promoter →	+0.062	+0.688	.002	.001	3	15
BONE	Protein-DNA complex organization →	+0.099	+0.759	<.001	.005	3	15
BLOOD_Lymphoma	Regulation of alternative mRNA splicing, via spliceosome →	+0.099	+0.815	<.001	.001	3	15
LIVER	Epigenetic regulation of gene expression →	+0.070	+1.176	<.001	.001	3	15
BREAST	mRNA alternative polyadenylation →	+0.087	+0.944	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,569 associations by consensus.

Positive regulation of gene expression, epigenetic by RBM4 expression — OVARY

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