RBM39

Across TCGA pan-cancer cohorts, RBM39 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated RBM39 data layer compared with 29 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher RBM39 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RBM39 expression acts as an unfavorable survival marker, although some lineages such as COAD and LUAD show a favorable association.

COAD, HNSC, and LUAD are the cancer types where RBM39 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.885	.026	12	view →
HNSC	DFS	Median	IV	0.701	0.899	.014	11	view →
LUAD	OS	Median	All	0.964	0.786	.033	7	view →
LSCC	OS	Quartile	II,III,IV	0.927	0.570	.025	5	view →
CCRCC	DFS	Quartile	All	0.878	1.000	.026	2	view →
PDAC	DFS	Tertile	All	0.913	0.753	.031	2	view →
GBM	OS	Quartile	All	0.509	0.281	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RBM39–COAD (DFS)

Open the COAD breakdown →