RBM38

Across TCGA patient cohorts, RBM38 mutation is significantly associated with the RNA expression of many other genes, with 233 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM38-associated genes across cancer lineages are RPS29P7, CCNG2P1, and RPS20P25. Each is linked with RBM38 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM38-to-partner and partner-to-RBM38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS29P7 grouped by RBM38-low versus RBM38-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM38→partner) and Y-score (partner→RBM38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RPS29P7 →	+0.249	+4.381	.002	.006	3	2
SKCM	CCNG2P1 →	+0.063	+4.440	<.001	.006	3	2
LUSC	RPS20P25 →	+0.137	+5.211	<.001	.007	3	2
BRCA	MIR548AP →	+0.317	+8.055	<.001	.007	3	1
UCEC	PDLIM1P1 →	+0.336	+2.627	.003	.006	3	1
UCEC	CHCHD2P3 →	+0.156	+2.188	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 233 associations by consensus.

RPS29P7 by RBM38 expression — SKCM

Explore this box plot interactively →