RBM38

Across TCGA patient cohorts, RBM38 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM38-associated genes across cancer lineages are NF2, Annexin-1, and ERK2. Each is linked with RBM38 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM38-to-partner and partner-to-RBM38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NF2 grouped by RBM38-low versus RBM38-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM38→partner) and Y-score (partner→RBM38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NF2 →	+0.370	+3.000	.001	.036	3	1
UCEC	Annexin-1 →	+0.823	+3.169	.004	.020	3	1
UCEC	ERK2 →	+0.299	+3.000	.004	.036	2	1
UCEC	ARID1A →	-0.367	-3.162	<.001	.019	1	1
UCEC	Cyclin-B1 →	+0.811	+3.169	.008	.020	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

NF2 by RBM38 expression — UCEC

Explore this box plot interactively →