RBM38

Across TCGA cell cohorts, RBM38 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,465 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RBM38-associated GO terms across cancer lineages are Transcription initiation-coupled chromatin remodeling, Negative regulation of RNA catabolic process, and Regulation of transcription initiation by RNA polymerase II. Each is linked with RBM38 in more than 12 cancer types. Because this analysis shows association rather than direction, both RBM38-to-partner and partner-to-RBM38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription initiation-coupled chromatin remodeling grouped by RBM38-low versus RBM38-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM38→partner) and Y-score (partner→RBM38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Transcription initiation-coupled chromatin remodeling →	+0.074	+0.773	<.001	<.001	3	13
SOFT_TISSUE	Negative regulation of RNA catabolic process →	+0.083	+1.577	<.001	<.001	3	13
SOFT_TISSUE	Regulation of transcription initiation by RNA polymerase II →	+0.055	+1.145	<.001	<.001	3	12
SOFT_TISSUE	Positive regulation of transcription initiation by RNA polymerase II →	+0.058	+0.934	<.001	<.001	3	12
LIVER	Regulation of mRNA catabolic process →	+0.068	+1.614	.001	.001	3	12
LIVER	Regulation of DNA repair →	+0.077	+1.645	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,465 associations by consensus.

Transcription initiation-coupled chromatin remodeling by RBM38 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →