RBM34

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RBM34 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM34-associated genes across cancer lineages are ERK2, FoxM1, and S6_pS240_S244. Each is linked with RBM34 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM34-to-partner and partner-to-RBM34 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM34→partner) and Y-score (partner→RBM34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECERK2 →+0.203+2.321.019.03432
UCECFoxM1 →+0.240+2.700.039.00632
UCECS6_pS240_S244 →+0.398+3.000.029.03632
UCECA-Raf_pS299 →-0.148-2.000.006.03231
UCECJNK_pT183_Y185 →-0.223-3.459.003.00531
UCECJNK2 →+0.295+2.700<.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration