RBM33

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RBM33 mutation is significantly associated with the RNA expression of many other genes, with 4,340 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM33-associated genes across cancer lineages are THRB, ATP5F1A, and BPNT1. Each is linked with RBM33 in more than 2 cancer types. Because this analysis shows association rather than direction, both RBM33-to-partner and partner-to-RBM33 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM33→partner) and Y-score (partner→RBM33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADTHRB →-0.829-2.793<.001.00333
COADATP5F1A →+0.529+2.624<.001.00533
UCECBPNT1 →+0.344+1.701.003.00133
UCECTCEA2 →-0.460-2.453<.001<.00133
UCECPSMD5 →+0.450+2.567<.001<.00133
UCECCENPM →+0.538+1.725<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,340 associations by consensus.

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