Across TCGA patient cohorts, RBM33 mutation is significantly associated with the total protein of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM33-associated genes across cancer lineages are eEF2, MEK1, and Notch1. Each is linked with RBM33 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM33-to-partner and partner-to-RBM33 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM33→partner) and Y-score (partner→RBM33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.207	+1.280	.029	.049	3	2
UCEC	MEK1 →	+0.347	+1.544	<.001	<.001	3	2
UCEC	Notch1 →	+0.122	+1.665	.001	.002	3	2
UCEC	p27_pT198 →	+0.057	+1.093	.042	.012	3	2
UCEC	Annexin-1 →	+0.481	+2.070	<.001	.001	3	2
UCEC	Chk2_pT68 →	-0.163	-2.710	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

Exploration

RBM33 survival (RNA) · tumor vs normal (RNA) · all RBM33 data types