RBM3

Across TCGA patient cohorts, RBM3 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,892 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RBM3-associated proteins across cancer lineages are HSP90B1_S447, PLCG2, and AFG3L2. Each is linked with RBM3 in more than 3 cancer types. Because this analysis shows association rather than direction, both RBM3-to-partner and partner-to-RBM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RBM3 versus HSP90B1_S447 in CCRCC, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM3→partner) and Y-score (partner→RBM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	HSP90B1_S447 →	-0.763	-0.446	<.001	.001	3	4
BRCA	PLCG2 →	-0.517	-0.381	<.001	.005	3	4
BRCA	AFG3L2 →	-0.472	-0.500	<.001	<.001	3	3
BRCA	AAMDC →	+0.518	+0.406	<.001	<.001	3	3
PDAC	NHSL2_T285 →	+0.525	+0.239	<.001	.007	3	3
BRCA	RPL7 →	-0.245	-0.318	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,892 associations by consensus.

RBM3 vs HSP90B1_S447 — CCRCC

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