RBM3

Across TCGA patient cohorts, RBM3 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM3-associated genes across cancer lineages are Ku80, PEA-15, and Tuberin. Each is linked with RBM3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM3-to-partner and partner-to-RBM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by RBM3-low versus RBM3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM3→partner) and Y-score (partner→RBM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.321	+2.179	.009	.034	3	1
UCEC	PEA-15 →	+0.221	+2.999	.024	.035	3	1
UCEC	Tuberin →	+0.405	+2.817	.004	.036	3	1
UCEC	Claudin-7 →	-0.523	-3.321	.048	.010	3	1
UCEC	beta-Catenin →	+0.609	+3.321	.021	.010	2	1
UCEC	DJ-1 →	+0.224	+3.321	.010	.010	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Ku80 by RBM3 expression — UCEC

Explore this box plot interactively →