RBM3

Across TCGA cell cohorts, RBM3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,107 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible RBM3-associated GO terms across cancer lineages are Lagging strand elongation, Positive regulation of chromosome condensation, and Positive regulation of synapse structural plasticity. Each is linked with RBM3 in more than 9 cancer types. Because this analysis shows association rather than direction, both RBM3-to-partner and partner-to-RBM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lagging strand elongation grouped by RBM3-low versus RBM3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM3→partner) and Y-score (partner→RBM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Lagging strand elongation →	+0.114	+0.570	.001	.004	2	10
KIDNEY	Positive regulation of chromosome condensation →	+0.150	+0.598	<.001	.008	3	8
LUNG_NSCLC_LUSC	Positive regulation of synapse structural plasticity →	+1.553	+1.811	<.001	<.001	3	8
BLOOD_Lymphoma	Negative regulation of heterochromatin organization →	+0.074	+0.585	<.001	.001	3	7
BLOOD_Lymphoma	Negative regulation of heterochromatin formation →	+0.074	+0.585	<.001	.001	3	7
UPPER_AERODIGESTIVE_TRACT	Pericentric heterochromatin formation →	+0.107	+0.797	.006	.009	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,107 associations by consensus.

Lagging strand elongation by RBM3 expression — STOMACH

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