RBM28

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RBM28 mutation is significantly associated with the RNA expression of many other genes, with 2,439 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM28-associated genes across cancer lineages are ABCD1P4, EIF3JP1, and MTND6P33. Each is linked with RBM28 in more than 2 cancer types. Because this analysis shows association rather than direction, both RBM28-to-partner and partner-to-RBM28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ABCD1P4 grouped by RBM28-low versus RBM28-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM28→partner) and Y-score (partner→RBM28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAABCD1P4 →+0.279+3.320<.001.00833
UCECEIF3JP1 →+0.199+2.005<.001.00433
BRCAMTND6P33 →+0.173+6.725.005<.00132
LIHCRNA5SP457 →+0.254+4.564<.001.00632
LIHCMYT1L-AS1 →+0.007+4.564<.001.00632
LIHCRNU6-1088P →+0.547+4.404<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,439 associations by consensus.

ABCD1P4 by RBM28 expression — BLCA

Box plot of ABCD1P4 in RBM28-low vs RBM28-high samples in BLCA.

Explore this box plot interactively →

Exploration