RBM28

Across TCGA cell cohorts, RBM28 mutation is significantly associated with the RNA expression of many other genes, with 59 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RBM28-associated genes across cancer lineages are OR11H1, OR4X2, and KRTAP17-1. Each is linked with RBM28 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM28-to-partner and partner-to-RBM28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11H1 grouped by RBM28-low versus RBM28-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM28→partner) and Y-score (partner→RBM28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR11H1 →	+0.063	+4.786	<.001	<.001	3	2
SOFT_TISSUE	OR4X2 →	+0.032	+5.369	<.001	.004	3	1
SOFT_TISSUE	KRTAP17-1 →	+0.016	+5.369	<.001	.004	3	1
SOFT_TISSUE	KRT33A →	+0.058	+4.930	<.001	.008	3	1
URINARY_TRACT	LRIT2 →	+0.027	+4.087	.001	.009	3	1
BLOOD_Leukemia	CST9L →	+0.411	+4.269	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

OR11H1 by RBM28 expression — BLOOD_Leukemia

Explore this box plot interactively →