RBM27

Across TCGA patient cohorts, RBM27 mutation is significantly associated with the RNA expression of many other genes, with 4,532 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM27-associated genes across cancer lineages are LIAS, TOMM22, and SLC25A17. Each is linked with RBM27 in more than 3 cancer types. Because this analysis shows association rather than direction, both RBM27-to-partner and partner-to-RBM27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LIAS grouped by RBM27-low versus RBM27-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM27→partner) and Y-score (partner→RBM27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LIAS →	+0.344	+1.909	<.001	<.001	3	4
UCEC	TOMM22 →	+0.346	+1.868	<.001	<.001	3	3
UCEC	SLC25A17 →	+0.337	+2.491	<.001	<.001	3	3
UCEC	GNPNAT1 →	+0.536	+1.868	<.001	<.001	3	3
UCEC	ADNP2 →	+0.606	+1.699	<.001	<.001	3	3
UCEC	BLOC1S6 →	+0.502	+2.290	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,532 associations by consensus.

LIAS by RBM27 expression — UCEC

Explore this box plot interactively →