RBM27

Across TCGA cell cohorts, RBM27 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible RBM27-associated genes across cancer lineages are GRIA2, ACOD1, and GTSF1L. Each is linked with RBM27 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM27-to-partner and partner-to-RBM27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GRIA2 grouped by RBM27-low versus RBM27-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM27→partner) and Y-score (partner→RBM27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GRIA2 →	+0.088	+3.617	<.001	.004	3	2
PANCREAS	ACOD1 →	+0.053	+4.035	<.001	.003	3	1
PANCREAS	GTSF1L →	+0.038	+4.029	<.001	.007	3	1
PANCREAS	WNT9B →	+0.008	+4.029	<.001	.007	3	1
PANCREAS	TAS2R1 →	+0.067	+3.491	<.001	.008	3	1
PANCREAS	C12orf40 →	+0.039	+3.786	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

GRIA2 by RBM27 expression — LARGE_INTESTINE

Explore this box plot interactively →