RBM27

Across TCGA cell cohorts, RBM27 mutation is significantly associated with the mutation status of many other genes, with 2,485 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RBM27-associated genes across cancer lineages are WNK3, GRIN3A, and ZFC3H1. Each is linked with RBM27 in more than 5 cancer types. Because this analysis shows association rather than direction, both RBM27-to-partner and partner-to-RBM27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WNK3 grouped by RBM27-low versus RBM27-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM27→partner) and Y-score (partner→RBM27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	WNK3 →	+5.321	+5.894	.002	.002	1	6
BLOOD_Lymphoma	GRIN3A →	+4.754	+3.362	.002	.002	1	5
LARGE_INTESTINE	ZFC3H1 →	+1.884	+3.064	.003	.003	1	5
LARGE_INTESTINE	KDM6A →	+2.152	+2.787	.005	.005	1	5
LARGE_INTESTINE	LRRK1 →	+1.678	+2.865	.006	.006	1	5
PANCREAS	AKAP12 →	+3.906	+3.906	.003	.003	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,485 associations by consensus.

WNK3 by RBM27 expression — BLOOD_Leukemia

Explore this box plot interactively →