RBM25

Across TCGA cell cohorts, RBM25 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,119 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RBM25-associated GO terms across cancer lineages are Replication fork processing, Regulation of mRNA splicing, via spliceosome, and DNA-templated DNA replication maintenance of fidelity. Each is linked with RBM25 in more than 19 cancer types. Because this analysis shows association rather than direction, both RBM25-to-partner and partner-to-RBM25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Replication fork processing grouped by RBM25-low versus RBM25-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM25→partner) and Y-score (partner→RBM25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Replication fork processing →	+0.103	+0.988	.002	.005	3	20
UPPER_AERODIGESTIVE_TRACT	Regulation of mRNA splicing, via spliceosome →	+0.104	+1.213	<.001	<.001	3	20
LUNG_SCLC	DNA-templated DNA replication maintenance of fidelity →	+0.105	+0.870	<.001	<.001	3	19
SOFT_TISSUE	Microtubule nucleation →	+0.113	+1.059	<.001	<.001	3	19
URINARY_TRACT	Negative regulation of RNA splicing →	+0.106	+0.828	<.001	<.001	3	18
OESOPHAGUS	Regulation of alternative mRNA splicing, via spliceosome →	+0.125	+1.001	<.001	.003	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,119 associations by consensus.

Replication fork processing by RBM25 expression — BLOOD_Myeloma

Explore this box plot interactively →