RBM24

Across TCGA patient cohorts, RBM24 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM24-associated genes across cancer lineages are FASN, MEK1, and EGFR_pY1068. Each is linked with RBM24 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM24-to-partner and partner-to-RBM24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FASN grouped by RBM24-low versus RBM24-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM24→partner) and Y-score (partner→RBM24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FASN →	+0.322	+1.502	.026	.030	3	2
UCEC	MEK1 →	+0.418	+2.906	.001	.001	3	2
UCEC	EGFR_pY1068 →	-0.262	-1.502	.004	.030	3	1
UCEC	FoxM1 →	+0.213	+1.502	.025	.030	3	1
UCEC	ACC1 →	+0.393	+2.598	.003	.005	3	1
UCEC	Ku80 →	+0.187	+1.861	.031	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

FASN by RBM24 expression — UCEC

Explore this box plot interactively →