RBM22

Across TCGA patient cohorts, RBM22 protein abundance is significantly associated with the RNA expression of many other genes, with 18,184 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RBM22-associated genes across cancer lineages are HELLS, ATAD5, and PRIM1. Each is linked with RBM22 in more than 6 cancer types. Because this analysis shows association rather than direction, both RBM22-to-partner and partner-to-RBM22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RBM22 versus HELLS in HNSC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM22→partner) and Y-score (partner→RBM22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HELLS →	+0.713	+0.160	<.001	<.001	3	7
LSCC	ATAD5 →	+0.915	+0.208	<.001	<.001	3	7
LSCC	PRIM1 →	+0.867	+0.262	<.001	<.001	3	7
UCEC	LIG1 →	+0.829	+0.198	<.001	<.001	3	6
HNSC	SRSF3 →	+0.384	+0.142	.006	.001	3	6
HNSC	SNRPE →	+0.750	+0.184	.002	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,184 associations by consensus.

RBM22 vs HELLS — HNSC

Explore this scatter interactively →