RBM22

Across TCGA cell cohorts, RBM22 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,639 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RBM22-associated GO terms across cancer lineages are Positive regulation of RNA splicing, Positive regulation of organelle assembly, and Regulation of DNA-templated transcription initiation. Each is linked with RBM22 in more than 13 cancer types. Because this analysis shows association rather than direction, both RBM22-to-partner and partner-to-RBM22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of RNA splicing grouped by RBM22-low versus RBM22-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM22→partner) and Y-score (partner→RBM22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of RNA splicing →	+0.121	+0.650	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of organelle assembly →	+0.071	+0.929	<.001	.001	3	13
PANCREAS	Regulation of DNA-templated transcription initiation →	+0.085	+0.666	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Nucleic acid transport →	+0.093	+0.905	.001	.002	3	13
UPPER_AERODIGESTIVE_TRACT	RNA transport →	+0.093	+0.905	.001	.002	3	13
PANCREAS	RNA export from nucleus →	+0.111	+0.609	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,639 associations by consensus.

Positive regulation of RNA splicing by RBM22 expression — OESOPHAGUS

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