RBM20

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RBM20 mutation is significantly associated with the RNA expression of many other genes, with 1,060 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM20-associated genes across cancer lineages are RNU6-1101P, RN7SKP256, and UBE2F. Each is linked with RBM20 in more than 2 cancer types. Because this analysis shows association rather than direction, both RBM20-to-partner and partner-to-RBM20 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM20→partner) and Y-score (partner→RBM20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRNU6-1101P →+0.296+4.757<.001.00433
BRCARN7SKP256 →+1.364+4.209<.001.00932
COADUBE2F →+0.389+3.472.001.00232
UCECAP1S3 →+0.443+2.415.003.00332
UCECCXCL13 →+1.786+2.263<.001<.00132
UCECABHD3 →+0.616+3.828<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,060 associations by consensus.

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