Across TCGA cell cohorts, RBM20 mutation is significantly associated with the RNA expression of many other genes, with 504 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RBM20-associated genes across cancer lineages are SPANXN5, CD300H, and SCGB3A2. Each is linked with RBM20 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM20-to-partner and partner-to-RBM20 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM20→partner) and Y-score (partner→RBM20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	SPANXN5 →	+0.068	+3.684	<.001	.001	3	2
LARGE_INTESTINE	CD300H →	+0.018	+2.830	<.001	.004	3	2
OESOPHAGUS	SCGB3A2 →	+0.665	+4.017	.002	.007	3	1
SOFT_TISSUE	CLEC6A →	+0.022	+3.635	.009	.007	3	1
SOFT_TISSUE	C11orf97 →	+0.182	+4.169	<.001	.002	3	1
URINARY_TRACT	OR2A2 →	+0.046	+5.087	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 504 associations by consensus.

Exploration

RBM20 survival (RNA) · tumor vs normal (RNA) · all RBM20 data types