RBM18

Across TCGA cell cohorts, RBM18 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,957 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RBM18-associated GO terms across cancer lineages are Proteasome regulatory particle assembly, Positive regulation of mRNA 3'-end processing, and Proteasome assembly. Each is linked with RBM18 in more than 15 cancer types. Because this analysis shows association rather than direction, both RBM18-to-partner and partner-to-RBM18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proteasome regulatory particle assembly grouped by RBM18-low versus RBM18-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM18→partner) and Y-score (partner→RBM18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Proteasome regulatory particle assembly →	+0.213	+0.908	<.001	<.001	3	16
OESOPHAGUS	Positive regulation of mRNA 3'-end processing →	+0.128	+0.802	.004	.001	3	16
OVARY	Proteasome assembly →	+0.116	+0.773	<.001	<.001	3	13
BLOOD_Lymphoma	Protein autoubiquitination →	+0.054	+0.719	<.001	<.001	3	13
LIVER	Positive regulation of RNA splicing →	+0.101	+0.782	<.001	.002	2	13
PANCREAS	Import into nucleus →	+0.055	+0.592	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,957 associations by consensus.

Proteasome regulatory particle assembly by RBM18 expression — LIVER

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