RBM17

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RBM17 mutation is significantly associated with the RNA expression of many other genes, with 1,221 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM17-associated genes across cancer lineages are RN7SKP229, RNU6-306P, and PDE4B-AS1. Each is linked with RBM17 in more than 2 cancer types. Because this analysis shows association rather than direction, both RBM17-to-partner and partner-to-RBM17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP229 grouped by RBM17-low versus RBM17-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM17→partner) and Y-score (partner→RBM17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRN7SKP229 →+0.312+5.087<.001.00233
LIHCRNU6-306P →+0.403+5.544<.001.00432
LIHCPDE4B-AS1 →+0.173+6.676<.001<.00132
UCECTRAJ11 →+0.553+2.228<.001.00132
UCECRNA5SP418 →+0.863+2.278<.001.00132
UCECRNA5SP422 →+1.146+2.671<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,221 associations by consensus.

RN7SKP229 by RBM17 expression — COAD

Box plot of RN7SKP229 in RBM17-low vs RBM17-high samples in COAD.

Explore this box plot interactively →

Exploration