RBM17

Across TCGA cell cohorts, RBM17 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,153 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RBM17-associated GO terms across cancer lineages are Positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, Positive regulation of DNA-templated DNA replication, and Replication fork processing. Each is linked with RBM17 in more than 15 cancer types. Because this analysis shows association rather than direction, both RBM17-to-partner and partner-to-RBM17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay grouped by RBM17-low versus RBM17-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM17→partner) and Y-score (partner→RBM17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.128	+0.879	<.001	<.001	3	16
BONE	Positive regulation of DNA-templated DNA replication →	+0.092	+0.602	.006	.002	3	15
PANCREAS	Replication fork processing →	+0.108	+1.003	<.001	<.001	3	15
SOFT_TISSUE	Subtelomeric heterochromatin formation →	+0.102	+0.590	<.001	<.001	3	15
BONE	Regulation of sister chromatid cohesion →	+0.134	+1.019	.002	.002	2	15
SOFT_TISSUE	DNA replication checkpoint signaling →	+0.136	+0.651	.002	.006	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,153 associations by consensus.

Positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay by RBM17 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →