RBM15

Across TCGA cell cohorts, RBM15 mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RBM15-associated genes across cancer lineages are OR2J2, IL9, and GLT6D1. Each is linked with RBM15 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM15-to-partner and partner-to-RBM15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2J2 grouped by RBM15-low versus RBM15-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM15→partner) and Y-score (partner→RBM15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	OR2J2 →	+0.013	+5.087	<.001	.004	3	2
URINARY_TRACT	IL9 →	+0.130	+5.087	<.001	.004	3	1
URINARY_TRACT	GLT6D1 →	+0.026	+5.087	<.001	.004	3	1
BLOOD_Leukemia	NPPB →	+0.087	+3.662	<.001	.003	3	1
BLOOD_Leukemia	SOWAHB →	+0.039	+4.108	<.001	<.001	3	1
BLOOD_Leukemia	CGB8 →	+0.041	+2.966	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

OR2J2 by RBM15 expression — URINARY_TRACT

Explore this box plot interactively →