RBM14

Across TCGA patient cohorts, RBM14 mutation is significantly associated with the RNA expression of many other genes, with 2,782 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM14-associated genes across cancer lineages are OR6K3, IZUMO3, and RNA5SP237. Each is linked with RBM14 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM14-to-partner and partner-to-RBM14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6K3 grouped by RBM14-low versus RBM14-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM14→partner) and Y-score (partner→RBM14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	OR6K3 →	+0.047	+5.039	.005	.008	3	2
LUAD	IZUMO3 →	+0.177	+4.418	<.001	.006	3	2
READ	RNA5SP237 →	+0.374	+6.681	<.001	<.001	3	2
READ	HMGB3P3 →	+0.118	+6.257	<.001	.001	3	2
UCEC	CCDC43 →	+0.609	+2.032	<.001	<.001	3	2
UCEC	GINS3 →	+0.476	+2.021	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,782 associations by consensus.

OR6K3 by RBM14 expression — READ

Explore this box plot interactively →