RBM14

Across TCGA patient cohorts, RBM14 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM14-associated genes across cancer lineages are Notch1, PCNA, and Cyclin-B1. Each is linked with RBM14 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM14-to-partner and partner-to-RBM14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by RBM14-low versus RBM14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM14→partner) and Y-score (partner→RBM14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.142	+2.097	.002	.003	3	2
UCEC	PCNA →	+0.194	+1.584	.007	.009	3	2
UCEC	Cyclin-B1 →	+0.647	+3.700	<.001	.001	3	2
UCEC	ERK2 →	+0.151	+1.584	.019	.034	3	1
UCEC	ACC_pS79 →	+0.265	+2.584	.022	.010	3	1
UCEC	GAPDH →	+0.367	+1.584	.041	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Notch1 by RBM14 expression — UCEC

Explore this box plot interactively →