RBM14

Across TCGA cell cohorts, RBM14 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RBM14-associated genes across cancer lineages are AVP, GALNTL5, and SMYD1. Each is linked with RBM14 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM14-to-partner and partner-to-RBM14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by RBM14-low versus RBM14-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM14→partner) and Y-score (partner→RBM14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AVP →	+0.056	+3.632	<.001	.003	3	1
BREAST	GALNTL5 →	+0.281	+3.963	.001	.003	3	1
BREAST	SMYD1 →	+0.238	+4.115	<.001	.002	3	1
BREAST	TMIGD1 →	+0.018	+3.672	<.001	.006	3	1
BREAST	RTP5 →	+0.031	+3.672	<.001	.006	3	1
BLOOD_Leukemia	CST8 →	+0.034	+3.969	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

AVP by RBM14 expression — LARGE_INTESTINE

Explore this box plot interactively →