RBM12B

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RBM12B mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM12B-associated genes across cancer lineages are INPP4B, ATM, and GAPDH. Each is linked with RBM12B in more than 2 cancer types. Because this analysis shows association rather than direction, both RBM12B-to-partner and partner-to-RBM12B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM12B→partner) and Y-score (partner→RBM12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECINPP4B →-0.286-2.169.005.00233
UCECATM →-0.623-2.378<.001<.00133
COADGAPDH →+0.615+2.820.013.03532
UCECJNK2 →+0.232+2.058<.001<.00132
UCECNotch1 →+0.155+1.523<.001.00832
UCECPDCD4 →-0.496-1.523<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Exploration