Across TCGA cell cohorts, RBM12B mutation is significantly associated with the RNA expression of many other genes, with 321 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RBM12B-associated genes across cancer lineages are ALDH6A1, NABP2, and WRAP53. Each is linked with RBM12B in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM12B-to-partner and partner-to-RBM12B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM12B→partner) and Y-score (partner→RBM12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ALDH6A1 →	+1.202	+3.212	<.001	.006	3	2
LARGE_INTESTINE	NABP2 →	+0.477	+3.385	.005	.004	3	2
LARGE_INTESTINE	WRAP53 →	+0.564	+3.212	.005	.006	3	2
LARGE_INTESTINE	TIFA →	+0.798	+3.212	.006	.006	3	2
LARGE_INTESTINE	CYB5D1 →	+1.115	+3.234	<.001	.004	3	2
LARGE_INTESTINE	HSD17B6 →	+1.401	+3.299	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 321 associations by consensus.

Exploration

RBM12B survival (RNA) · tumor vs normal (RNA) · all RBM12B data types