RBM12B-AS1

Across TCGA pan-cancer cohorts, RBM12B-AS1 RNA differs between tumor and matched normal tissue in 17 of 18 cancer types tested, making tumor–normal expression one of RBM12B-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RBM12B-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RBM12B-AS1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

HNSC, BLCA, and LUAD are the cancer types where RBM12B-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RBM12B-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	IV	+0.738	<.001	12	view →
BLCA	All	All	+0.866	<.001	9	view →
LUAD	Male	All	+0.865	<.001	9	view →
KIRC	All	All	+0.256	<.001	9	view →
STAD	Male	II,III,IV	+1.048	<.001	8	view →
UCEC	All	All	+0.622	.003	8	view →
LIHC	All	All	+0.305	<.001	8	view →
COAD	Female	II,III,IV	+0.732	<.001	7	view →
LUSC	Female	All	+0.994	<.001	6	view →
BRCA	All	II,III,IV	+0.665	<.001	6	view →
KIRP	Male	III,IV	+0.467	.007	6	view →
THCA	All	II,III,IV	−0.499	.001	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 17 lineages.

RBM12B-AS1–HNSC

Open the HNSC breakdown →