RBM12

Across TCGA patient cohorts, RBM12 mutation is significantly associated with the RNA expression of many other genes, with 3,165 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM12-associated genes across cancer lineages are MIR4510, MIR551A, and BANF1P5. Each is linked with RBM12 in more than 2 cancer types. Because this analysis shows association rather than direction, both RBM12-to-partner and partner-to-RBM12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4510 grouped by RBM12-low versus RBM12-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM12→partner) and Y-score (partner→RBM12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR4510 →	+0.238	+4.757	<.001	.004	3	3
BRCA	MIR551A →	+0.238	+4.162	.001	.009	3	3
READ	BANF1P5 →	+0.194	+5.219	<.001	.006	3	3
BRCA	FKBP4P8 →	+0.023	+4.215	<.001	.009	3	2
UCEC	PLTP →	-0.817	-2.000	<.001	<.001	3	2
UCEC	CORO2B →	-0.513	-2.652	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,165 associations by consensus.

MIR4510 by RBM12 expression — CESC

Explore this box plot interactively →