RBL1

Across TCGA patient cohorts, RBL1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,924 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RBL1-associated genes across cancer lineages are FOXM1, MCM8, and SPC25. Each is linked with RBL1 in more than 4 cancer types. Because this analysis shows association rather than direction, both RBL1-to-partner and partner-to-RBL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RBL1 versus FOXM1 in GBM, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBL1→partner) and Y-score (partner→RBL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FOXM1 →	+1.351	+0.743	<.001	<.001	3	5
UCEC	MCM8 →	+0.850	+0.539	.008	.008	3	5
GBM	SPC25 →	+1.342	+0.636	.005	.001	3	5
GBM	GINS1 →	+0.990	+0.605	<.001	<.001	3	4
GBM	MYBL2 →	+1.798	+0.843	<.001	<.001	3	4
GBM	E2F1 →	+1.177	+0.585	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,924 associations by consensus.

RBL1 vs FOXM1 — GBM

Explore this scatter interactively →