RBL1

Across TCGA cell cohorts, RBL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,690 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RBL1-associated GO terms across cancer lineages are Regulation of mitotic sister chromatid separation, Positive regulation of cell cycle checkpoint, and Positive regulation of cell cycle. Each is linked with RBL1 in more than 18 cancer types. Because this analysis shows association rather than direction, both RBL1-to-partner and partner-to-RBL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitotic sister chromatid separation grouped by RBL1-low versus RBL1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBL1→partner) and Y-score (partner→RBL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of mitotic sister chromatid separation →	+0.135	+1.056	<.001	<.001	3	19
SKIN	Positive regulation of cell cycle checkpoint →	+0.148	+1.038	<.001	<.001	3	19
OESOPHAGUS	Positive regulation of cell cycle →	+0.106	+1.192	.001	.004	3	19
OESOPHAGUS	Mitotic sister chromatid segregation →	+0.120	+1.092	.003	<.001	3	19
OESOPHAGUS	Chromosome segregation →	+0.144	+1.296	.002	<.001	3	19
OESOPHAGUS	Nuclear chromosome segregation →	+0.155	+1.230	.001	.002	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,690 associations by consensus.

Regulation of mitotic sister chromatid separation by RBL1 expression — OVARY

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