RBKS

Across TCGA pan-cancer cohorts, RBKS mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RBKS data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher RBKS mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RBKS expression acts as an unfavorable survival marker, although some lineages such as PDAC and LUAD show a favorable association.

PDAC, LUAD, and HNSC are the cancer types where RBKS mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Tertile	II,III,IV	0.918	0.564	.002	34	view →
LUAD	DFS	Median	II,III,IV	0.768	0.246	.019	8	view →
HNSC	DFS	Quartile	All	0.895	1.000	.016	4	view →
CCRCC	OS	Tertile	II,III,IV	0.985	0.133	.027	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RBKS–PDAC (DFS)

Open the PDAC breakdown →