RBKS

Across TCGA patient cohorts, RBKS protein abundance is significantly associated with the RNA expression of many other genes, with 17,098 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RBKS-associated genes across cancer lineages are ANKRD31, CFAP221, and GINS1. Each is linked with RBKS in more than 5 cancer types. Because this analysis shows association rather than direction, both RBKS-to-partner and partner-to-RBKS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RBKS versus ANKRD31 in UCEC, with a Pearson correlation of 0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBKS→partner) and Y-score (partner→RBKS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ANKRD31 →	+0.526	+0.515	.004	<.001	3	6
LUAD	CFAP221 →	+0.903	+0.255	.002	.004	3	6
LSCC	GINS1 →	-1.039	-0.467	<.001	<.001	3	5
GBM	NCAPG →	-0.928	-0.417	<.001	<.001	3	5
UCEC	DNAH6 →	+1.434	+0.577	<.001	<.001	3	5
BRCA	NCAPH →	-0.860	-0.659	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,098 associations by consensus.

RBKS vs ANKRD31 — UCEC

Explore this scatter interactively →