RBFOX3

Across TCGA patient cohorts, RBFOX3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,752 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RBFOX3-associated genes across cancer lineages are SHISAL1, CPLX1, and CMAS. Each is linked with RBFOX3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBFOX3-to-partner and partner-to-RBFOX3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RBFOX3 versus SHISAL1 in UCEC, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBFOX3→partner) and Y-score (partner→RBFOX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SHISAL1 →	+1.584	+0.845	.009	.004	3	2
GBM	CPLX1 →	+1.878	+0.826	<.001	<.001	3	2
UCEC	CMAS →	-0.773	-0.756	.004	.001	3	1
UCEC	SOBP →	+1.383	+1.044	.001	.004	3	1
UCEC	PALLD →	+1.179	+0.973	.009	<.001	3	1
UCEC	PSAT1 →	-2.028	-0.835	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,752 associations by consensus.

RBFOX3 vs SHISAL1 — UCEC

Explore this scatter interactively →