RBFOX2

Across TCGA pan-cancer cohorts, RBFOX2 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated RBFOX2 data layer compared with 26 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher RBFOX2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RBFOX2 expression acts as an unfavorable survival marker, although some lineages such as OV show a favorable association.

LUAD, OV, and CCRCC are the cancer types where RBFOX2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.877	1.000	.001	37	view →
OV	DFS	Median	All	1.000	0.693	.046	4	view →
CCRCC	OS	Median	II,III,IV	0.277	0.972	.010	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

RBFOX2–LUAD (OS)

Open the LUAD breakdown →