RBFOX2

Across TCGA cell cohorts, RBFOX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,419 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RBFOX2-associated GO terms across cancer lineages are Negative regulation of cilium assembly, Caveolin-mediated endocytosis, and Negative regulation of DNA-templated transcription initiation. Each is linked with RBFOX2 in more than 15 cancer types. Because this analysis shows association rather than direction, both RBFOX2-to-partner and partner-to-RBFOX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cilium assembly grouped by RBFOX2-low versus RBFOX2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBFOX2→partner) and Y-score (partner→RBFOX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Negative regulation of cilium assembly →	+0.089	+1.331	<.001	<.001	3	16
KIDNEY	Caveolin-mediated endocytosis →	+0.206	+1.124	<.001	<.001	3	15
STOMACH	Negative regulation of DNA-templated transcription initiation →	+0.153	+1.080	<.001	.006	3	15
STOMACH	Negative regulation of transcription initiation by RNA polymerase II →	+0.153	+1.080	<.001	.006	3	15
STOMACH	Regulation of organelle assembly →	+0.045	+0.859	<.001	.002	3	14
LUNG_NSCLC_LUSC	Negative regulation of organelle assembly →	+0.116	+1.034	<.001	.002	2	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,419 associations by consensus.

Negative regulation of cilium assembly by RBFOX2 expression — LIVER

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