RBFA

Across TCGA patient cohorts, RBFA protein abundance is significantly associated with the RNA expression of many other genes, with 2,720 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RBFA-associated genes across cancer lineages are RAB27A, SNRNP27, and ADCY4. Each is linked with RBFA in more than 2 cancer types. Because this analysis shows association rather than direction, both RBFA-to-partner and partner-to-RBFA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RBFA versus RAB27A in BRCA, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBFA→partner) and Y-score (partner→RBFA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RAB27A →	-0.646	-0.329	<.001	<.001	3	3
UCEC	SNRNP27 →	-0.362	-0.319	<.001	.005	3	2
UCEC	ADCY4 →	-0.462	-0.262	.002	<.001	3	2
BRCA	PPP1R18 →	-0.500	-0.257	<.001	<.001	3	2
BRCA	TRIP4 →	-0.385	-0.337	<.001	<.001	3	2
PDAC	SELPLG →	-0.648	-0.371	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,720 associations by consensus.

RBFA vs RAB27A — BRCA

Explore this scatter interactively →