RBBP9

Across TCGA pan-cancer cohorts, RBBP9 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RBBP9 data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RBBP9 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RBBP9 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and GBM show a favorable association.

CCRCC, UCEC, and GBM are the cancer types where RBBP9 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.928	0.128	.014	20	view →
UCEC	DFS	Tertile	III,IV	0.350	1.000	.013	12	view →
GBM	OS	Quartile	All	0.658	0.319	.001	11	view →
HNSC	OS	Quartile	All	0.938	1.000	.031	3	view →
PDAC	OS	Quartile	All	0.763	0.582	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RBBP9–CCRCC (DFS)

Open the CCRCC breakdown →