RBBP8NL

Across TCGA pan-cancer cohorts, RBBP8NL mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RBBP8NL’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RBBP8NL mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types RBBP8NL is over-expressed in tumor, although a few such as HNSC show the opposite, repressed pattern.

HNSC, LSCC, and LUAD are the cancer types where RBBP8NL tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RBBP8NL mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	All	−1.228	<.001	12	view →
LSCC	All	All	+0.399	<.001	6	view →
LUAD	Female	All	+0.360	.003	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

RBBP8NL–HNSC

Open the HNSC breakdown →