RBBP5

Across TCGA patient cohorts, RBBP5 mutation is significantly associated with the RNA expression of many other genes, with 2,899 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBBP5-associated genes across cancer lineages are WBP1LP6, RNA5SP321, and RNA5SP204. Each is linked with RBBP5 in more than 2 cancer types. Because this analysis shows association rather than direction, both RBBP5-to-partner and partner-to-RBBP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WBP1LP6 grouped by RBBP5-low versus RBBP5-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBBP5→partner) and Y-score (partner→RBBP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	WBP1LP6 →	+0.053	+4.469	<.001	.006	3	3
CESC	RNA5SP321 →	+0.325	+5.539	<.001	.004	3	2
UCEC	RNA5SP204 →	+0.320	+1.640	<.001	.009	3	2
SKCM	LINC02272 →	+0.032	+4.624	<.001	.005	3	2
LUSC	HMGN1P19 →	+0.211	+5.038	<.001	.009	3	2
SKCM	RN7SL837P →	+0.089	+4.993	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,899 associations by consensus.

WBP1LP6 by RBBP5 expression — SKCM

Explore this box plot interactively →