RBBP4P1

Across TCGA pan-cancer cohorts, RBBP4P1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of RBBP4P1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RBBP4P1 RNA is repressed in tumor relative to normal tissue. In most cancer types RBBP4P1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KICH, BLCA, and COAD are the cancer types where RBBP4P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RBBP4P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	−0.452	<.001	10	view →
BLCA	All	III,IV	+0.490	<.001	8	view →
COAD	All	II,III,IV	+0.387	<.001	8	view →
BRCA	All	II,III,IV	+0.280	<.001	6	view →
LIHC	All	All	+0.142	.001	5	view →
LUSC	Female	All	+0.577	<.001	4	view →
LUAD	Male	All	+0.538	<.001	4	view →
STAD	All	II,III,IV	+0.538	.001	4	view →
CHOL	All	All	+0.383	.001	2	view →
KIRP	All	IV	+0.279	.040	2	view →
PRAD	All	All	+0.184	.031	2	view →
HNSC	All	All	+0.121	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

RBBP4P1–KICH

Open the KICH breakdown →