RBBP4

Across TCGA patient cohorts, RBBP4 mutation is significantly associated with the RNA expression of many other genes, with 2,750 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBBP4-associated genes across cancer lineages are RNA5SP422, RNA5SP70, and RNA5SP414. Each is linked with RBBP4 in more than 2 cancer types. Because this analysis shows association rather than direction, both RBBP4-to-partner and partner-to-RBBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP422 grouped by RBBP4-low versus RBBP4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBBP4→partner) and Y-score (partner→RBBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP422 →	+0.986	+2.323	<.001	<.001	3	3
BRCA	RNA5SP70 →	+0.458	+6.731	<.001	<.001	3	3
UCEC	RNA5SP414 →	+0.655	+2.670	<.001	<.001	3	3
UCEC	RNA5SP412 →	+0.703	+2.619	<.001	<.001	3	3
CESC	LINC02563 →	+0.630	+4.757	<.001	.004	3	2
CESC	NIFKP1 →	+0.051	+3.975	.007	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,750 associations by consensus.

RNA5SP422 by RBBP4 expression — UCEC

Explore this box plot interactively →