RBBP4

Across TCGA cell cohorts, RBBP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,720 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RBBP4-associated GO terms across cancer lineages are Negative regulation of cell cycle phase transition, Microtubule cytoskeleton organization involved in mitosis, and DNA-templated DNA replication. Each is linked with RBBP4 in more than 14 cancer types. Because this analysis shows association rather than direction, both RBBP4-to-partner and partner-to-RBBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell cycle phase transition grouped by RBBP4-low versus RBBP4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBBP4→partner) and Y-score (partner→RBBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell cycle phase transition →	+0.091	+1.252	<.001	<.001	3	15
SOFT_TISSUE	Microtubule cytoskeleton organization involved in mitosis →	+0.101	+1.006	.001	<.001	3	15
BONE	DNA-templated DNA replication →	+0.150	+1.338	.004	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell cycle process →	+0.090	+1.439	<.001	<.001	3	14
BONE	Double-strand break repair via break-induced replication →	+0.257	+1.334	.005	.001	3	14
KIDNEY	Spindle assembly →	+0.068	+0.805	.003	.006	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,720 associations by consensus.

Negative regulation of cell cycle phase transition by RBBP4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →