RBAKDN

Across TCGA pan-cancer cohorts, RBAKDN RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of RBAKDN’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RBAKDN RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RBAKDN is over-expressed in tumor.

HNSC, COAD, and BRCA are the cancer types where RBAKDN tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RBAKDN RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.539	<.001	10	view →
COAD	Male	III,IV	+0.408	<.001	8	view →
BRCA	All	All	+0.208	<.001	6	view →
LUSC	Male	All	+0.367	<.001	4	view →
UCEC	All	All	+0.376	.018	2	view →
BLCA	All	All	+0.345	.022	2	view →
LUAD	All	All	+0.265	.013	2	view →
CHOL	All	All	+0.202	.006	2	view →
LIHC	All	II,III,IV	+0.065	.020	2	view →
KIRC	Male	All	+0.060	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

RBAKDN–HNSC

Open the HNSC breakdown →